Vyvanse is a brand name medication containing Lisdexamfetamine. It is useful to treat attention deficit hyperactivity disorder in people over five years of age and mild to severe binge eating disorder in adults.
Vyvanse is an oral medication with the onset of effects within 2 hours and a duration of about 12 hours. As per DEA (Drug Enforcement Administration), medicine has a high potential for abuse. Vyvanse is a stimulant medication that stimulates the central nervous system after being converted into dextroamphetamine by the body.
The chemical composition of Lisdexamfetamine has the amino acid L-lysine attached to the dextroamphetamine. It got approval for medical use in 2007 in the United States. Vyvanse is one of the most prescribed medications in the United States, with more than 5 million prescriptions per year.
The DEA put Vyvanse as a Schedule-II controlled substance under the controlled substance act.
Vyvanse is mainly useful as a treatment for binge eating disorder and attention deficit hyperactivity disorder. Like all other amphetamines, it has similar off-label uses. No clinical trials demonstrate the safety of Lisdexamfetamine for ADHD treatment.
Vyvanse contraindicated in people with:
- Hypersensitivity to Lisdexamfetamine
- Known sensitivity to its inactive ingredient
- Use of monoamine oxidase inhibitor
- A history of drug abuse
- Heart disease
- Severe agitation
- Severe hypertension
The Food and Drug Administration advises individuals with depression, bipolar disorder, liver or kidney problems, elevated blood pressure, psychosis, mania, seizures, Raynaud’s phenomenon, tics, thyroid problems, or Tourette syndrome to monitor the symptoms while taking Vyvanse. People with these medical conditions should buy Vyvanse online only when prescribed by a doctor, and its potential benefits outweigh the potential risks.
Vyvanse causes several side effects along with its therapeutic effects. Common adverse effects of Vyvanse include:
- Cardiovascular effects including hypertension or hypotension, Raynaud’s phenomenon, tachycardia
- Males have sexual side effects like erectile dysfunction, prolonged or frequent erection
- Gastrointestinal side effects include constipation, abdominal pain, nausea, diarrhea
- Other potential adverse effects are appetite loss, dry mouth, blurred vision, excessive teeth grinding, profuse sweating, nosebleed, reduced seizure threshold, weight loss, and tics.
Psychological side effects of Vyvanse include increased self-confidence, apprehension, alertness, concentration, mood swings, initiative, sociability, insomnia, or decreased sense of fatigue. Less common psychological effects include:
- Obsessive behavior
- Change in libido
Vyvanse overdose leads to many different symptoms, but it is rarely fatal with appropriate and timely care. The intensity of overdose symptoms increases with dose and decreases with tolerance to the medication. A manifestation of moderate to extremely large overdose includes abnormal heartbeat, high or low blood pressure, confusion, severe agitation, abnormally fast reflexes, tremor, muscle pain, rapid breathing, urinary retention, painful urination, mydriasis, and elevated body temperature.
Vyvanse has a potential for abuse like other central nervous system stimulants. People abuse the medication not to get Vyvanse high; instead, they report that it makes them feel more energetic and focused. It doesn’t give a high like marijuana or other abused substances.
The medication is a schedule-II controlled substance, which means that it has a high potential for severe addiction and abuse. It causes euphoria or other desirable effects, which leads to Vyvanse addiction. A person using Vyvanse at therapeutic doses has a lower risk of addiction than someone who is abusing the medication.
Long-term high doses of the medication can develop tolerance and dependence that eventually results in addiction. Vyvanse addiction treatment and recovery require specialized care and individualized approach.
Adderall vs. Vyvanse
Comparing Adderall vs. Vyvanse:
- Adderall is a combination of amphetamine (dextroamphetamine and levoamphetamine) salts, while Vyvanse contains Lisdexamfetamine.
- Vyvanse has less potential for abuse than Adderall as it is a prodrug which gets converted into dextroamphetamine in the body.
- Both Adderall and Vyvanse have similar effects and efficacy because they both contain amphetamines.
- Though Vyvanse and Adderall both have amphetamine, the former has comparatively lesser potential for risks as its active ingredient does not directly act on the brain. Lisdexamfetamine in Vyvanse first gets converted to dextroamphetamine, while Adderall contains dextroamphetamine and levoamphetamine that directly works in the brain to cause more significant adverse effects.